Primary Ano-rectal Melanoma- A Rare but lethal entity

Authors

  • Mohd. Iqbal Lone Department of Pathology SKIMS, Srinagar J&K India.

Abstract

Background: Primary ano-rectal malignant melanoma (ARMM) is rare but aggressive tumor. After skin and retina though this is the third most common site of melanoma. It accounts only for approximately 0.5% of all colorectal or anal cancers. Symptoms include passing of blood with stools, anal pain, and changes in bowel habits or rectal mass.

Material and methods: The study was carried in the department of pathology sher-i-Kashmir institute of medical sciences soura Srinagar. A total of five cases that underwent surgery for anorectal mass and diagnosed as primary anorectal melanoma were included in the study. Retrospective records of 8 years (January 2010 to December 2017) were examined.

Results: 5 cases of ano-rectal malignant melanoma were identified. Out of 5 patients, 60% were females and 40% were male patients. Age of the patients ranged from 60-75 yrs. The commonest presenting symptom was blood with stools 60% of the patients. Most of the patients at the time of diagnosis had Stage III disease (60%) with nodal metastasis in all the patients. The commonest histological variant seen was epitheloid variant of malignant melanoma (3 cases).

Conclusion:  Elderly patients presenting with non-specific symptoms like melena, mass prolapse, and abnormal bowel habits: malignant melanoma should always be kept as one of the differential diagnosis.

Key words:  Melanoma, APR, Melena, IHC, WLE

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Published

2018-10-28

How to Cite

Mohd. Iqbal Lone. (2018). Primary Ano-rectal Melanoma- A Rare but lethal entity. International Journal of Medical Science And Diagnosis Research, 2(5). Retrieved from https://ijmsdr.com/index.php/ijmsdr/article/view/93

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Articles