International Journal of Medical Science And Diagnosis Research <p><strong>International Journal of Medical Science And Diagnosis Research</strong>&nbsp;<strong>(IJMSDR)</strong>&nbsp;is a online and print version cum open-access journal.&nbsp;<strong>IJMSDR</strong>&nbsp;serves the world's research and scholarly communities and aims to be one of the largest publishers for professional and scholarly societies.&nbsp;<strong>IJMSDR's</strong>&nbsp;journals maintain the highest standards of peer review, with some internationally-recognized editors serving on the editorial boards of&nbsp;<strong>IJMSDR's&nbsp;</strong>journals.<strong>IJMSDR</strong>&nbsp;is not only a publisher, but also a hub for Scientists, Academician, and Research Scholars.&nbsp;<strong>IJMSDR</strong>&nbsp;is a platform offering excellent resources for different research fields. It connects traditional publishing with the opportunities afforded by new technologies. Through publishing with&nbsp;<strong>IJMSDR,</strong>your work can enjoy worldwide reach and you can get a quick response from your colleagues worldwide.&nbsp;<strong>IJMSDR</strong>&nbsp;is a world’s most prestigious learned groups and publishers. Our goal is to bring high quality research work. Other than publications of journals &amp; Books, we also provide&nbsp;some subsidiary Products, Tools, Technology and Services like Thesis, Dissertation Project formatting and publishing etc.&nbsp;</p> <p>These&nbsp;scholarly open access medical journals&nbsp;aim to contribute to the progress and application of scientific discoveries, by providing free access to the research information.&nbsp;The published work reaches the general public and the scientific community immediately after publication, thus providing higher citation rates for the author.&nbsp;</p> IJMSDR en-US International Journal of Medical Science And Diagnosis Research 2589-7837 Silk Dye Effluent Induced Change in Ultra-Structure of Testis on Swiss Albino Male Mice Mus Musculus and Recovery by Moringa Oleifera Leaves Powder <p style="font-weight: 400;">The silk dye effluent is one of the most potential harmful chemicals liberated in the environment in an unexpected manner. Silk dye waste is widely used as a potent dyeing of yarn and fabrics in many countries and has been shown to produce some adverse health effects. This work focuses primarily on the effects of <em>Moringa oleifera</em> leaf extract on testis of silk dye effluent induced surface ultrastructure in Swiss albino mice <em>Mus musculus</em>. The testis has been taken an account for surface ultrastructural study. The mice were divided into 5 Groups i.e. Group I (Control), Group II (fed with 50% silk dye), Group III (fed with 100% silk dye), Group IV (mice fed with 50% dye treated with <em>M. oleifera</em> leaves powder), Group V (mice fed with 100% dye treated with <em>M. oleifera</em> leaves powder) have been taken for experiment. The dose of silk dye was 2ml/day to both groups II and III and <em>M. oleifera</em> leaf is given as per the standard dose (300mg/kg b.w) to both animals of group IV and V. Administration of silk dye waste result were demonstrated disrupted spermatids, cessation of seminiferous tubule cell, irregular cavity, lump of seminiferous tubules, disrupted interstitial cell and occupied spermatogonial cells but used of <em>Moringa oleifera</em> leafs powder it was significantly recovered the damage tissues has been observed. This study suggested that the extract may have beneficial effect on surface ultrastructural constituents such as Testis.</p> <p><strong>Key words: </strong>Silk dye Effluent, <em>Moringa oleifera</em> leaf powder, Testis, <em>Mus musculus</em>, SEM for Ultra-Structure, Toxicity assessment.</p> Serina Khatun Copyright (c) 2023 International Journal of Medical Science And Diagnosis Research 2023-09-06 2023-09-06 7 5 10.32553/ijmsdr.v7i5.989 Asymptomatic Apical Hypertrophic Cardiomyopathy: Case Report and Review of Literature <p style="font-weight: 400;">Apical hypertrophic cardiomyopathy (AHCM) is a known entity since its first introduction by Sakamoto and Yamaguchi. However, unlike classical hypertrophic cardiomyopathy (HCM), it is less explored in terms of its associated diagnosis and long-term outcomes. Given the increased availability and utilization of ultra-sophisticated cardiac imaging modalities, AHCM will be increasingly recognized as a distinct, clinically significant variant of classical HCM. It is associated with a wide spectrum of presentation ranging from asymptomatic course with incidental findings on imaging to rarely being associated with ventricular arrhythmias, syncope and sudden cardiac death (SCD). Contrast echocardiography is the most effective and diagnostic study when performed in the right setting with high suspicion on clinical and typical electrocardiogram (ECG) findings. Cardiac magnetic resonance imaging (CMR) has an equal diagnostic yield as a contrast echocardiogram. We are presenting a unique case report of a 57-year old gentleman with asymptomatic AHCM which was distinctly delineated after utilizing contrast tuned imaging (CnTI) echocardiography sans administration of intravenous contrast agents. This is a first case report of AHCM portrayed by this ingenious technology.</p> <p><strong>Keywords: </strong>Apical Hypertrophic Cardiomyopathy, LV Contrast Echocardiography, Contrast Tuned Imaging, 4Dimensional XStrain Echocardiography.</p> Akhil Mehrotra Anurag Mehrotra Mohammed Shaban Shubham Kacker Copyright (c) 2023 International Journal of Medical Science And Diagnosis Research 2023-09-06 2023-09-06 7 5 10.32553/ijmsdr.v7i5.990