BACTERIOLOGICAL & CLINICAL PROFILE OF PRIMARY PYODERMA AND ITS ASSOCIATION WITH NASAL CARRIAGE
Abstract
Background: Pyodermas (pyogenic infection of skin) are one of the most common clinical conditions encountered in dermatological practice. Staphylococcus aureus (S. aureus) accounts for 30-50% of skin and soft tissue infections (SSTI), followed by the other bacteria. It is observed that nasal colonization with S. aureus occurs in up to 40% of patient population. Though there are many studies on nasal flora in normal and pyoderma patients, only few studies have compared the isolates from both sites in same patient. This study was conducted to determine, whether the isolates from both the sites are common in phenotypic characters and antimicrobial susceptibility pattern.
Materials and methods: The prospective study was done in the Department of Microbiology and Dermatology from September 2017 to August 2018.Pus Samples received in the microbiology laboratory was further processed according to standard microbiological techniques. Antimicrobial Susceptibility testing was performed by Kirby Bauer disc diffusion method. Zone diameters were interpreted according to CLSI guidelines.
Results: A total of 75 primary pyoderma cases and nasal samples were recruited for the study.
Majority of the samples collected for this study were from patients in the age group of 11-20 years
Among the primary skin infections, majority of patients had furuncle followed by folliculitis. Staphylococcus aureus was the predominant isolate followed by Coagulase negative Staphylococcus spp both in pus and nasal cultures. 42 (56%) samples yielded the growth of same organisms which were also same in their phenotypic characters and antibiotic sensitivity pattern. MRSA strains were 34(45.3%) in pus samples and 26(34.6%) in nasal specimens.
Conclusion: Correlation between organisms isolated from lesions and their carriage in the nasal specimen is very important for adequate treatment and also to prevent recurrent pyodermas caused by resistant organism
Keywords: PYODERMA - STAPHYLOCOCCUS AUREUS - MRSA - NASAL CARRIAGE –
