UTILIZATION OF POLYMER AND LIPID-BASED DRUG DELIVERY SYSTEMS IN TREATMENT OF NEUROLOGICAL DISORDERS- A MINI REVIEW
DOI:
https://doi.org/10.32553/ijmsdr.v4i11.700Keywords:
Neurological disorder, Lipid, Polymer, Lipid Based Drug delivery systems, Epilepsy, TreatmentAbstract
In modern drug discovery techniques consistently increasing in the number of new pharmacologically active lipid compounds these compounds are poorly water-soluble. A great challenge of making this medication for oral administration with the desired bioavailability. Epilepsy is a severe neurological disorder that needs rapid treatment. To enhancement of its bioavailability, we need to make lipid-based drugs. On other hand, the surface tension reducing agents will give poor water-soluble formulation. Treatment of Neurological disorder is still a challenge for medical practitioners because of restricted moments and barriers. The solid lipid nanoparticles (SLN) and nanoemulsions are easily avoided the blood-brain barrier. Therefore, there is a maximum therapeutic efficacy achieved by using the lipid and polymer-based drug delivery system in the treatment of neurological disorders.
Keywords: Neurological disorder, Lipid, Polymer, Lipid Based Drug delivery systems, Epilepsy, Treatment.